My research interests lie in the field of marine molecular cytogenetics and genomics, shellfish aquaculture and oyster breeding.
At the moment, the focus of my research is to better understand the loss of chromosomes from polyploid oysters that are often associated with cytological problems. In order to do so, I apply the main molecular cytogenetic tools, flow cytometry and confocal microscopy to visualize centrosomes and microtubules behavior in detail, during the early development of polyploid oysters.
The loss of chromosomes from polyploid oysters is of major scientific interest and of practical concern for commercial oyster culture.
PhD Marine Biology (2014) - University of Western Brittany, Ifremer UMR 6539, France and Portuguese Institute for the Ocean and Atmosphere (IPMA) Portugal
Master degree in Developmental Biology (2010) - Lusófona University and Portuguese Institute for the Ocean and Atmosphere (IPMA) Portugal
Degree in Biology (2008) - Lusófona University, Lisbon, Portugal
de Sousa JT, Allen Jr. SK, Wolfe BM, Small JM. 2017. Mitotic instability in triploid and tetraploid one‐year old Eastern oyster, Crassostrea virginica, assessed by cytogenetic and flow cytometry techniques. Genome 61:79-89
de Sousa JT, Allen SK, Baker H, Matt JL. 2016. Aneuploid progeny of the American oyster, Crassostrea virginica, produced by tetraploid × diploid crosses: another example of chromosome instability in polyploid oysters. Genome 59: 327–338.
de Sousa JT, Milan M, Pauletto M, Bargelloni L, Joaquim S, Matias, D, Matias, AM, Quillien, V, Leitão, A, Huvet, A (2015). A microarray-based analysis of oocyte quality in the European clam Ruditapes decussatus. Aquaculture 446, 17–24.
de Sousa JT, Milan M, Bargelloni L, Pauletto M., Matias D., Joaquim S., Matias AM, Quillien V., Leitão L., Huvet A. (2014). A Microarray-Based Analysis of Gametogenesis in Two Portuguese Populations of the European Clam Ruditapes decussatus. PLoS ONE 9:e92202
Joana Teixeira de Sousa, Domitília Matias, Sandra Joaquim, Radhouan Ben Hamadou and Alexandra Leitão. (2012). “Preferential chromosome loss in aneuploid metaphases of Crassostrea angulata and Ruditapes decussatus”. Aquaculture, 344–349, pp.239-241
Joana Teixeira de Sousa, Domitília Matias, Sandra Joaquim, Radhouan Ben Hamadou and Alexandra Leitão. (2011). “Growth variation in bivalves: “New insights into growth, physiology and somatic aneuploidy in the carpet shell Ruditapes decussatus”. Journal of Experimental Marine Biology and Ecology. Journal of Experimental Marine Biology and Ecology 406, pp. 46–53